Paramyxoviridae Use Distinct Virus-Specific Mechanisms to Circumvent the Interferon Response
نویسندگان
چکیده
منابع مشابه
Virus-driven conditional expression of an interferon antagonist as a tool to circumvent host restriction.
H osts and viruses are under a constant coevolution pressure. Schematically, a virus (as a population) requires a permanent supply of naive hosts to continue to exist, and survival of the host population relies on its ability to develop antiviral defenses. Severe acute respiratory syndrome coronavirus, Henipaviruses (Hendra and Nipah) and filoviruses (Ebola and Marburg) are apt examples. On the...
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The production of interferon (IFN) was investigated in human peripheral lymphocyte cultures stimulated by mumps virus. IFN-alpha and IFN-gamma were produced in lymphocyte cultures from immune donors. However, no IFN-gamma was produced in lymphocyte cultures from nonimmune donors. IFN-alpha was produced by B lymphocytes, and IFN-gamma was produced by T lymphocytes. An increase in the production ...
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ژورنال
عنوان ژورنال: Virology
سال: 2000
ISSN: 0042-6822
DOI: 10.1006/viro.2000.0240